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PANP-006A
Insulin β Chain Peptide (15 - 23)
Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly
Size:1mg
P1(RMB):275
MW:1009.2
One letter sequence:LYLVCGERG
Molecular Formula:
Description:This peptide also known as INS is the 15-23 fragment of the insulin β chain recognized by islet-associated T cells. It was used in diabetes studies to assay the IFN-β and IL-17 production by diabetogenic CD4 or CD8 T cells. This peptide stains the INS-reactive CTL clone, but doesn’t stain the splenic CD8+ T cells from NOD or 8.3-TCR-transgenic NOD mice.
Literature Reference:Hu, C. et al. J. Clin. Invest. 117, 3857 (2007) Amrani, A. et al. Nature 406, 739 (2000).
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