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CRFS-004A
a-Helical Corticotropin Releasing Factor (9-41)
Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2
Size:0.5mg
P1(RMB):460
MW:3826.4
One letter sequence:DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH2
Molecular Formula:C166H274N46O53S2
Description:CRF antagonist, lyophilized solid that acts as a potent antagonist to CRF receptors to block the behavioral and physiological responses to a stressor when administered in the CNS.
Literature Reference:J. Rivier et al., Science, 224, 889 (1984)
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