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GALA-004B
M35
Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-NH2
Size:1.0mg
P1(RMB):828
MW:2233.6
One letter sequence:GWTLNSAGYLLGPPPGFSPFR-NH2
Molecular Formula:C107H153N27O26
Description:Galanin antagonist that binds with high specificity and affinity to galanin binding sites and provides a new principle in the treatment of dementia and related disorders. At low concentrations, this chimeric peptide antagonizes the effect of galanin, whereas at concentrations above 10nM M35 it acts as a galanin receptor agonist.
Literature Reference:K. Kask et al., Regulatory Peptide, 59, 341 (1995)
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