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GALA-005A
M40
Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2
Size:0.5mg
P1(RMB):460
MW:1981.3
One letter sequence:GWTLNSAGYLLGPPPALALA-NH2
Molecular Formula:C94H145N23O24
Description:Antagonist of galanin receptor that significantly antagonizes galanin-induced feeding behavior at doses approximately equimolar to the active doses of rat galanin. It inhibits the binding of (125I-Tyr26)-galanin (porcine) in rat hypothalamic membranes with IC50 value of 15nM.
Literature Reference:S.F. Leibowitz et al., Brain Res., 599, 148 (1992); J.N. Crawley et al., Brain Res., 600, 268 (1993); X. J. Xu et al., Br. J. Pharmacol., 116, 2076 (1995)
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